Two recent scientific advances now give us the knowledge to attack the basic causes of chronic, severe pain rather than just prescribe symptomatic relief.
1. An immune, inflammatory cell called the "microglia" causes inflammation inside the brain and spinal cord when it is activated by a painful injury, disease, or trauma. This inflammation is called "neuroinflammation" as it is confined to the central nervous system (CNS) which is the brain, spinal cord, and cauda equina (nerve roots). Neuroinflammation traps the bioenergy of pain in a process called centralization thereby producing constant, severe, suffering pain.
2. Neurons and nerve cells may regrow and the process is called neurogenesis. Brain and spinal cord make a set of "neurohormones" to accomplish this task. These hormones include estradiol, DHEA, pregnenolone, progesterone, human chorionic gonadotropin, oxytocin, and human growth hormone.
The etiologic or curative approach to severe, chronic pain is to eliminate or reduce neuroinflammation while simultaneously promoting neurogenesis.